Table 1.
Comparison of baseline data stratified by the neutrophil count.
| Variables | All subjects, n = 221 | Higher neutrophil, n = 109 | Lower neutrophil, n = 112 | P-value |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age, years | 65.9 ± 13.1 | 65.8 ± 13.6 | 66.0 ± 12.7 | 0.925 |
| Male, n (%) | 135 (61.1) | 67 (61.5) | 68 (60.7) | 0.909 |
| Risk factors | ||||
| Hypertension, n (%) | 137 (62.0) | 67 (61.5) | 70 (62.5) | 0.874 |
| Diabetes mellitus, n (%) | 56 (25.3) | 34 (31.2) | 22 (19.6) | 0.048 |
| Hyperlipidemia, n (%) | 20 (9.0) | 12 (11.0) | 8 (7.1) | 0.317 |
| Coronary heart disease, n (%) | 23 (10.4) | 14 (12.8) | 9 (8.0) | 0.242 |
| Current smoker, n (%) | 79 (35.7) | 36 (33.0) | 43 (38.4) | 0.405 |
| Clinical data | ||||
| Systolic blood pressure, mmHg | 152.8 ± 23.7 | 151.8 ± 22.7 | 153.7 ± 22.8 | 0.548 |
| Diastolic blood pressure, mmHg | 80.5 ± 13.3 | 79.8 ± 12.6 | 81.2 ± 14.0 | 0.448 |
| Onset to groin puncture, min | 225.0 (189.0, 270.0) | 221.0 (188.0, 283.0) | 225.0 (188.5, 250.0) | 0.578 |
| Baseline NIHSS, score | 15.0 (11.0, 20.0) | 17.0 (12.0, 20.0) | 14.0 (10.0, 17.0) | 0.003 |
| Baseline ASPECTS, score | 9.0 (9.0, 10.0) | 9.0 (9.0, 10.0) | 9.0 (9.0, 10.0) | 0.907 |
| ICSA (vs. Non-ICAS), n (%) | 81 (36.3) | 49 (45.0) | 32 (28.6) | 0.012 |
| ICA (vs. MCA), n (%) | 84 (38.0) | 63 (57.8) | 74 (66.1) | 0.205 |
| Prior IVT, n (%) | 148 (67.0) | 71 (65.1) | 77 (68.8) | 0.568 |
| Poor collateral status, n (%) | 90 (40.7) | 40 (40.4) | 46 (41.1) | 0.915 |
| Stent retriever with rescue therapy, n (%) | 61 (27.6) | 32 (29.4) | 29 (25.9) | 0.565 |
| Passes with retriever | 2.0 (1.0, 2.0) | 2.0 (1.0, 2.0) | 2.0 (1.0, 2.0) | 0.218 |
| Successful reperfusion, n (%) | 165 (74.7) | 76 (69.7) | 89 (79.5) | 0.106 |
| sICH, n (%) | 22 (10.0) | 15 (13.8) | 7 (6.3) | 0.062 |
| Poor outcome at 90 days | 120 (54.3) | 72 (66.1) | 48 (42.9) | 0.001 |
| Laboratory data | ||||
| Total cholesterol, mmol/L | 4.1 ± 1.0 | 4.0 ± 0.9 | 4.1 ± 1.1 | 0.531 |
| Triglyceride, mmol/L | 1.6 (1.3, 3.1) | 1.7 (1.3, 2.2) | 1.6 (1.3, 1.9) | 0.520 |
| Low density lipoprotein, mmol/L | 3.0 (2.4, 3.5) | 3.0 (2.5, 3.7) | 2.9 (2.5, 3.3) | 0.235 |
| High density lipoprotein, mmol/L | 1.2 (1.1, 1.3) | 1.2 (1.1, 1.3) | 1.2 (1.1, 1.4) | 0.163 |
| Baseline blood glucose, mmol/L | 7.9 ± 3.1 | 8.2 ± 3.1 | 7.9 ± 3.0 | 0.504 |
| Hs-CRP, mg/L | 1.8 (1.2, 3.5) | 1.8 (1.2, 3.9) | 2.0 (1.4, 3.2) | 0.318 |
| Platelet, 109/L | 180.6 ± 70.2 | 184.3 ± 77.3 | 176.5 ± 62.7 | 0.383 |
ASPECTS, alberta stroke program early computed tomography score; Hs-CRP, hyper-sensitive C-reactive protein; ICAS, intracranial atherosclerotic stenosis; ICA, internal carotid artery; IVT, intravenous thrombolysis; MCA, middle cerebral artery; NIHSS, national institute of health stroke scale; sICH, symptomatic intracranial hemorrhage.