Table 2.
Comparison of baseline data in patients with and without unfavorable outcome at 90 days.
| Variables | Poor outcome, n = 120 | Good outcome, n = 101 | P-value |
|---|---|---|---|
| Demographic characteristics | |||
| Age, years | 65.8 ± 14.2 | 65.9 ± 11.8 | 0.978 |
| Male, n (%) | 70 (58.3) | 65(64.4) | 0.360 |
| Risk factors | |||
| Hypertension, n (%) | 78 (65.0) | 59 (58.4) | 0.315 |
| Diabetes mellitus, n (%) | 37 (30.8) | 19 (18.8) | 0.041 |
| Hyperlipidemia, n (%) | 12 (10.2) | 8 (7.9) | 0.591 |
| Coronary heart disease, n (%) | 14 (11.7) | 9 (8.9) | 0.504 |
| Current smoker, n (%) | 43 (35.8) | 36 (35.6) | 0.977 |
| Clinical data | |||
| Systolic blood pressure, mmHg | 154.6 ± 23.9 | 150.5 ± 23.4 | 0.199 |
| Diastolic blood pressure, mmHg | 81.4 ± 13.5 | 79.4 ± 13.1 | 0.269 |
| Onset to groin puncture, min | 240.0 (209.0, 283.0) | 215.0 (176.0, 248.0) | <0.001 |
| Baseline NIHSS, score | 16.0 (11.0, 21.0) | 14.0 (10.0, 17.0) | 0.002 |
| Baseline ASPECTS, score | 9.0 (8.0, 10.0) | 10.0 (9.0, 10.0) | 0.003 |
| ICSA (vs. Non-ICAS), n (%) | 54 (45.0) | 27 (26.7) | 0.005 |
| ICA (vs. MCA), n (%) | 54 (45.0) | 30 (29.7) | 0.022 |
| Prior IVT, n (%) | 76 (63.3) | 72 (71.3) | 0.210 |
| Poor collateral status, n (%) | 66 (55.0) | 24 (23.8) | <0.001 |
| Stent retriever with rescue therapy, n (%) | 35 (29.2) | 26 (25.7) | 0.571 |
| sICH, n (%) | 21 (17.5) | 1 (1.0) | <0.001 |
| Passes with retriever | 2.0 (1.0, 2.0) | 2.0 (1.0, 2.0) | 0.013 |
| Successful reperfusion, n (%) | 70 (58.3) | 95 (94.1) | <0.001 |
| Laboratory data | |||
| Total cholesterol, mmol/L | 4.0 ± 1.1 | 4.1 ± 1.0 | 0.367 |
| Triglyceride, mmol/L | 1.7 (1.2, 2.2) | 1.6 (1.4, 1.9) | 0.381 |
| Low density lipoprotein, mmol/L | 2.8 (2.5, 3.7) | 3.2 (2.6, 3.3) | 0.671 |
| High density lipoprotein, mmol/L | 1.2 (1.1, 1.2) | 1.2 (1.1, 1.4) | 0.107 |
| Baseline blood glucose, mmol/L | 8.3 ± 3.1 | 7.8 ± 3.2 | 0.350 |
| Hs-CRP, mg/L | 1.8 (1.2, 5.4) | 2.3 (1.3, 3.0) | 0.892 |
| Platelet, 109/L | 179.1 ± 75.4 | 182.3 ± 63.8 | 0.743 |
| Neutrophil count, 109/L | 6.7 ± 3.0 | 5.3 ± 2.1 | <0.001 |
ASPECTS, alberta stroke program early computed tomography score; Hs-CRP, hyper-sensitive C-reactive protein; ICAS, intracranial atherosclerotic stenosis; ICA, internal carotid artery; IVT, intravenous thrombolysis; MCA, middle cerebral artery; NIHSS, national institute of health stroke scale; sICH, symptomatic intracranial hemorrhage.