Table 3. Performance measures for optical diagnosis of SSL depending on lesion characteristics.

	Overall (n = 1396)	NICE type 1 (n = 335)	NICE type 2 /3 (n = 980)	1–5 mm (n = 898)	6–9 mm (n = 325)	> 10 mm (n = 166)	Proximal (n = 742)	Distal (n = 651)
Acc	92.0 (89.8–94.2)	84.2 (81.1–86.9)	94.8 (93.3–96.7)	93.4 (91.0–95.0)	89.5 (86.5–91.5)	88.5 (85.4–90.6)	91.9 (89.8–94.2)	92.0 (89.9–94.2)
S	32.9 (29.1–36.7)	43.2 (39.2–47.2)	23.3 (19.9–26.7)	14.7 (11.9–17.6)	34.5 (30.7–38.3)	68.7 (65.0–72.5)	53.3 (49.3–57.3)	5.9 (4.0–7.8)
E	95.5 (93.9–97.2)	90.4 (88.0–92.7)	97.0 (95.7–98.4)	96.5 (95.1–98.0)	94.9 (93.2–96.7)	90.7 (88.3–93.0)	94.4 (92.6–96.2)	96.8 (95.3–96.2)
PPV	30.6 (26.9–34.3)	40.4 (36.5–44.4)	20.0 (16.8–23.2)	14.3 (11.5–17.1)	40.0 (36.1–43.9)	44.0 (40.0–48.0)	38.1 (34.2–42.0)	9.1 (5.8–10.2)
NPV	95.6 (93.9–97.2)	91.3 (89.1–93.6)	97.6 (96.3–98.8)	96.7 (95.2–98.1)	93.7 (91.7–95.6)	96.4 (95.0–97.3)	96.9 (95.5–98.3)	94.9 (92.1–95.9)
LR +	7.35 (6.4–8.4)	4.5 (3.8–5.3)	7.9 (6.1–10.2)	4.2 (3.1–5.7)	6.8 (5.3–8.7)	7.4 (6.0–9.0)	9.5 (8.3–11.0)	1.8 (1.1–2.9)

NICE, NBI International Colorectal Endoscopic Classification; Acc, accuracy; S, sensitivity; E, specificity; PPV, positive predictive value; NPV, negative predictive value; LR + , positive likelihood ratio; data are given as% (95 % CI).