Fig. 1.

Vac pretreatment attenuates AP-induced acute liver injury in rats. (A and B) Serum ALT and AST levels. i. g and i. p represent oral gavage or intraperitoneal injection with a single dose of 2.0 g/kg or 1.0 g/kg of AP, respectively (n = 6–14). (C and D) Serum ALT, AST, hepatic H&E staining, and histology score in SD rats treated with Vac (100 mg/kg, twice a day) and/or with AP (i.g, 2.0 g/kg). n = 5–6 in Con or Vac group. n = 29 in AP and 20 in Vac_AP groups. Data were mean ± S.E.M. The magnification of H&E staining photograph is 200×. *P < 0.05; **P < 0.01.