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. Author manuscript; available in PMC: 2022 Jan 15.
Published in final edited form as: Ecotoxicol Environ Saf. 2020 Oct 16;208:111464. doi: 10.1016/j.ecoenv.2020.111464

Figure 3. HPA axis mediates PM2.5-induced pulmonary inflammation responses.

Figure 3.

A, female C57Bl/6J mice were performed with control sham surgery or bilateral total adrenalectomy, and their plasma corticosterone levels were assessed before and after fasting for 24 hours. n=10/group. *p<0.05 versus sham or versus before fasting, two-way ANOVA. B-E, 2 weeks after recovery from sham or bilateral total adrenalectomy surgery, mice were instilled with DEP suspension (200 μg in 50 μl/mouse), and BALF cell number (B), pulmonary inflammatory gene expressions (C, IL-1β; D, IL-6; E, TNF-α) were assessed using real time RT-PCR. n=10/group. *p<0.05, **p<0.01 versus sham or versus PBS, two-way ANOVA.