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. 2021 Jan 1;10:1. doi: 10.1038/s41377-020-00435-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a OPD images measured by DH (left) and ADRIFT-DH (right) in the MIR OFF state. The white, blue and green arrows show the existence of the nucleoli, nucleus and two particles, respectively. b Images of the photothermal OPD changes due to absorption of the MIR pump light measured by DH (left) and ADRIFT-DH (right). The area in the green dotted circle indicates the illumination spot of the MIR pump light. The structures indicated by the white (nucleoli), blue (nucleus) and green (particles) arrows in (a) also give stronger signals in the photothermal images shown in (b), which is visualized clearly with ADRIFT-DH but not with DH