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. 2020 Dec 9;5(12):1210–1224. doi: 10.1016/j.jacbts.2020.09.013

Figure 1.

Figure 1

Reduced Mortality in Nlrp3−/− Mice Following MI

(A) Mortality rates in wild-type (WT) (n = 23) and Nlrp3−/− (n = 24) male mice up to 7 days post-myocardial infarction (MI) (p = 0.048, by Kaplan-Meier analysis with log-rank test, 2 independent experiments combined). (B) Interleukin (IL)-18 levels in plasma measured by enzyme-linked immunosorbent assay 7 days post-MI (n = 9 mice per genotype). ∗p<0.05. (C and D) Left ventricle infarct size (representative image is shown, dashed line shows MI area) and ejection fraction measured 1 day post-MI by CMR (n = 17 mice per genotype). Values are presented as mean ± SEM.