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. 2020 Jan 23;106(1):87–97. doi: 10.3324/haematol.2019.239947

Figure 2.

Figure 2.

Effect of copy-number alterations on clinical outcome in chronic lymphocytic leukemia. Forest plot representing the results of univariable Cox regression analysis of copy-number alterations detected by array (with at least 10 events) and the effect of chronic lymphocytic leukemia (CLL) prognostic factors. A hazard ratio of less than 1.00 indicates a lower risk of overall survival. The size of each square is proportional to the amount of data available. U-CLL denotes patients with an unmutated immunoglobulin heavy chain variable gene and TP53abn denotes patients with del(17p) and/or a TP53 mutation. Loss13q.other are patients with a del(13q) not containing the established 13q14 minimally deleted region detectable by the diagnostic fluorescence in situ hybridization probe, and TRIS denotes patients with a trisomy. Only patients untreated at the date of DNA sampling were included for survival analysis. 95% CI: 95% confidence interval.