Figure 2.

Methylation of L1 and Alu elements by genomic feature in normal CD19⁺ B cells. Methylation (b) of retrotransposon probes by Alu (A) and L1 (B) subfamilies and genomic feature, as reported by the Illumina annotation file. Retrotransposon probes were categorised as those mapping to within 1,500 or 200 bases of the transcriptional start site (TSS1500, TSS200), the 5’ untranslated region (5’UTR), first exon (1^st exon), gene body (Body) and 3’ untranslated region (3’UTR). Lines indicate median values, boxes the interquartile range (IQR), whiskers the highest and lowest values within 1.5*IQR, and outliers are displayed as individual points.