Fig. 3.

Visualization of the anterior insula to nucleus accumbens tract.

(A) The AIns-NAcc tract in both hemispheres in a representative participant. The AIns-NAcc tract begins in the anterior insula and travels along the lateral-medial axis within subcaudate white matter until terminating in the NAcc (Leong et al., 2016, 2018). See Supplementary Fig. 3 for tract visualizations in additional participants. See also Supplementary Fig. 4 for the fiber orientation distribution in the voxels through which the AIns-NAcc tract travels.

(B) Tract profiles of AIns-NAcc tract fractional anisotropy (FA) along the trajectory of the tract. Mean diffusivity is also plotted to demonstrate the inverse relation between mean diffusivity and FA. The FA values in the middle 50% of the tract were averaged in each hemisphere separately to derive a measure of tract coherence in every participant.