Table 1.
Clinical characteristics and behavioral outcomes
| Visit 1 | Visit 2 | |||||
| Controls (n = 8) | Strokes (n = 9) | P | Controls (n = 6) | Strokes (n = 6) | P | |
| Age (mean years, SD) | 58.0 (13.1) | 59.8 (15.7) | 0.805 | |||
| Sex (n male, %) | 4 (50) | 4 (44) | 0.819 | |||
| Race (n black, %) | 2 (25) | 4 (44) | 0.402 | |||
| Handedness (n right, %) | 7 (88) | 9 (100) | 0.274 | |||
| Level of education (mean years, SD) | 18.6 (3.6) | 14.1 (4.4) | 0.036 | |||
| Occupation (level) | 0.266 | |||||
| History of dementia (n, %) | 0 (0) | 0 (0) | 1.000 | |||
| Family support (n, %) | 8 (100) | 7 (78) | 0.156 | |||
| Ambulation status (n walking, %) | 8 (100) | 9 (100) | 1.000 | |||
| Comorbidity index (mean points, SD) | 0.5 (1.4) | 2.2 (1.7) | 0.041 | |||
| Driving (n, %) | 8 (100) | 6 (67) | 0.072 | |||
| Hemisphere (n left, %) | 4 (44) | |||||
| Volume (mean cc, SD) | 2.8 (3.5) | |||||
| Time to the MEG (mean days, SD) | 51.4 (20.5) | 239.2 (12.5) | ||||
| Hours of sleep preimaging (mean hours, SD) | 7.1 (1.6) | 6.9 (2.0) | 0.841 | 6.6 (0.8) | 6.8 (2.2) | 0.801 |
| Clinical performance | ||||||
| NIHSS (mean points, SD) | 0 (0) | 0.7 (1.1) | 0.114 | 0 (0) | 0.2 (0.4) | 0.341 |
| mRS (median, IQR) | 0 (0) | 1.0 (0) | <0.001* | 0 (0) | 0.5 (1) | 0.046* |
| MoCA (median, IQR) | 29.5 (3) | 26.0 (4) | 0.005† | 29.5 (1) | 27.0 (3) | 0.221† |
| Barthel Index (mean points, SD) | 100 (0) | 100 (0) | 1.000 | 100 (0) | 100 (0) | 1.000 |
| F letters (mean n, SD) | 14.6 (4.1) | 14.1 (4.9) | 0.829 | 16.5 (4.0) | 15.6 (8.5) | 0.822 |
| S letters (mean n, SD) | 15.6 (3.2) | 15.8 (7.7) | 0.967 | 18.3 (5.5) | 15.4 (6.9) | 0.45 |
| Boys names (mean n, SD) | 19.9 (2.9) | 18.5 (7.5) | 0.636 | 22.5 (4.2) | 21.2 (8.5) | 0.748 |
| MEG visual comprehension task | ||||||
| Reaction time total (mean s, SD) | 0.8818 (0.2398) | 1.5343 (0.9247) | 0.0724 | 0.7615 (0.1590) | 1.1423 (0.5565) | 0.138 |
| Number incorrect total (mean n, SD) | 3.0 (1.2) | 9.7 (7.9) | 0.032 | 2.0 (1.3) | 13.8 (19.0) | 0.152 |
| Match mismatch | ||||||
| Reaction time total (mean s, SD) | 0.7155 (0.2349) | 1.3212 (1.0075) | 0.144 | 0.7127 (0.2088) | 0.9618 (0.6260) | 0.377 |
| Reaction time correct (mean s, SD) | 0.7132 (0.2339) | 1.2221 (0.9465) | 0.189 | 0.7129 (0.2085) | 0.9627 (0.6203) | 0.372 |
| Reaction time incorrect (mean s, SD) | 0.8651 (0.5379) | 1.9160 (1.7927) | 0.2915 | 0.5848 (0.1779) | 0.9606 (0.7679) | 0.449 |
| Number incorrect (mean n, SD) | 0.9 (0.7) | 3.6 (4.0) | 0.102 | 0.5 (0.0548) | 2.2 (2.1) | 0.094 |
| Pairs naming | ||||||
| Reaction time total (mean s, SD) | 0.8136 (0.1899) | 1.5333 (0.9062) | 0.044 | 0.7009 (0.1418) | 1.0225 (0.4157) | 0.103 |
| Reaction time correct (mean s, SD) | 0.8098 (0.1857) | 1.4536 (0.7162) | 0.026 | 0.7000 (0.1415) | 1.0501 (0.4783) | 0.116 |
| Reaction time incorrect (mean s, SD) | 1.2410 (0.2557) | 2.5409 (2.8480) | 0.471 | 0.8887 (0.0255) | 1.0144 (0.4146) | 0.702 |
| Number incorrect (mean n, SD) | 0.6 (0.9) | 2.6 (2.8) | 0.086 | 0.3 (0.5) | 5.7 (8.6) | 0.159 |
| Pairs description | ||||||
| Reaction time total (mean s, SD) | 1.1155 (0.3492) | 1.8096 (0.9939) | 0.081 | 0.8810 (0.1530) | 1.4776 (0.6289) | 0.048 |
| Reaction time correct (mean s, SD) | 1.1086 (0.3390) | 1.7149 (0.8194) | 0.071 | 0.8783 (0.1567) | 1.5103 (0.7136) | 0.06 |
| Reaction time incorrect (mean s, SD) | 1.3669 (0.8357) | 2.7742 (2.6739) | 0.175 | 0.9369 (0.2865) | 1.6812 (0.5598) | 0.0294 |
| Number incorrect (mean n, SD) | 1.6 (0.9) | 3.6 (2.9) | 0.094 | 1.2 (1.0) | 6 (8.5) | 0.195 |
Means compared using Student’s t test; percentages compared using χ2 analyses.
*
mRS 0 versus 1 compared using χ2 analysis.
†
MOCA scores compared using the Mann–Whitney U Test.