Table 5.
Altered susceptibility of P. aeruginosa PAO1 ∆arn to AZM
Mutant name | MIC, µg/mL | ||
MHB | RPMI | RPMI/serum | |
PAO1 | 128 | 8 | 2 |
∆arn | 64 | 8 | 1 |
∆arn+arn | 128 | 8 | 2 |
Bacteria were grown in MHB, RPMI+5%MHB (RPMI), and RPMI + 5% MHB + 20% human serum (RPMI/serum). MICs for deletion mutant (∆arn in which PA3552 to PA3558 were deleted) and the complemented mutant (∆arn+arn) compared to WT PAO1 are presented.