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Figure 8.

Figure 8.

Reciprocal regulation of glycolysis and gluconeogenesis. PFK1 and fructose 1,6-bisphosphate (F-2,6-BPase) are key regulatory enzymes in glycolysis and gluconeogenesis, respectively. AMP and F-2,6-BP activate PFK1 and inhibit F-2,6-BPase.