Table 1.
Patient characteristics and their status on the day of sampling.
| Total | Mild | Moderate | Severe | |
|---|---|---|---|---|
| Number | 105 | 74 | 19 | 12 |
| Age (years) | 53 (36–68) | 48(31–62) | 65 (48–74) | 68 (55–79) |
| Sex, male | 72 (68.6%) | 49 (66%) | 14 (74%) | 9 (75%) |
| Nationality, Japanese | 98 (93.3%) | 68 (92%) | 18 (95%) | 12 (100%) |
| Height (m) | 1.65 (1.60–1.72) | 1.65 (1.60–1.71) | 1.68 (1.58–1.74) | 1.66 (1.59–1.74) |
| Weight (kg) | 64.4 (53.5–75.0) | 64.4 (52.9–74.6) | 63.8 (50.7–75.2) | 65.6 (61.1–75.7) |
| Body mass index (kg/m2) | 22.7 (20.6–26.4) | 22.6 (20.4–26.2) | 22.2 (20.3–25.7) | 23.7 (21.7–27.1) |
| Past medical history | ||||
| Bronchial asthma | 6 (5.7%) | 5 (6.8%) | 1 (5.3%) | 1 (8.3%) |
| Cancer | 7 (6.7%) | 6 (8.1%) | 0 (0%) | 1 (8.3%) |
| Immunocompromised | 6 (5.7%) | 4 (5.4%) | 1 (5.3%) | 1 (8.3%) |
| Diabetes mellitus | 15 (14.3%) | 6 (8.1%) | 4 (21%) | 5 (41%) |
| Smoking | ||||
| Never | 47 (44.8%) | 36 (49%) | 6 (32%) | 5 (41%) |
| Current smoker | 24 (22.9%) | 16 (22%) | 6 (32%) | 2 (17%) |
| Ex-smoker | 22 (21.0%) | 14 (19%) | 5 (26%) | 3 (25%) |
| Unknown | 12 (11.4%) | 8 (11%) | 2 (11%) | 2 (17%) |
| Drugs with potential antiviral effects | 57 (54.3%) | 29 (39%) | 16 (84%) | 12 (100%) |
| Pneumonia | 86 (82.0%) | 55 (74%) | 19 (100%) | 12 (100%) |
| VTM samples, n | 229 | 166 | 40 | 23 |
| Day of illness on sampling day | 13 (9–17) | 13 (9–17) | 13 (11–18) | 17 (13–23) |
| Peak body temperature on sampling day | 36.6 (36.4–37.0) | 36.6 (36.4–36.9) | 36.6 (36.3–37.1) | 36.9 (36.5–37.6) |
| Respiratory rate at sampling | 18 16–18 | 17 (16–18) | 18 (16–20) | 20 (18–24) |
| Oxygen demand at sampling | 51 (22.2%) | 0 | 29 (72.5%) | 22 (95.7%) |
| Reagent samples, n | 40 | 36 | 4 | 0 |
| Day of illness on sampling day | 14 (9–18) | 13 (8–17) | 28 (25–35) | – |
| Peak body temperature on sampling day | 36.5 (36.3–36.6) | 36.5 (36.2–36.7) | 36.5 (36.3–36.6) | – |
| Respiratory rate at sampling | 17 (16–18) | 17 (16–18) | 17 (15–18) | – |
| Oxygen demand at sampling | 2 (5.0%) | 0 | 2 (50.0%) | – |
VTM, viral transport medium. Data are expressed as n (%) or median (interquartile range), or as specified.