Table 1.

Impact of Antimicrobial Resistance in Health Care Systems

Organisms	Threat Level	Estimated Cases in Hospitalized Patients (2017)	Estimated Deaths (2017)	Estimated Attributable Healthcare Costs (2017) US
Carbapenem-resistant Acinetobacter	Urgent	8,500	700	$281M
Clostridioides difficile	Urgent	223,900	12,800	$1B
Carbapenem-Resistant Enterobacteriaceae	Urgent	13,100	1,100	$130M
Drug-Resistant Neisseria gonorrhoeae	Urgent	550,000	1.14M	$133.4M
Vancomycin-Resistant Enterococci (VRE)	Serious	54,500	5,400	$539M
Multidrug-Resistant Pseudomonas aeruginosa	Serious	32,600	2,700	$767M
Methicillin-Resistant Staphylococcus aureus	Serious	323,700	10,600	$1.7B
Extended-Spectrum Beta-Lactamase (ESBL) Producing Enterobacteriaceae	Serious	197,400	9,100	$1.2B
Drug-Resistant Tuberculosis (Tb)	Serious	847	62	$164,000 Per MDR case $526,000 Per XDR case

Note: Data from Centers for Disease Control and Prevention.¹⁹