TABLE 1.
Initial Definitions of Transgressions in Physiologic Goals of Therapy
| Transgression Variable | Definition |
|---|---|
| Mean arterial pressure | < 80 mm Hg |
| Systolic blood pressure | |
| Low | < 100 mm Hg |
| High | > 180 mm Hg |
| Intracranial pressure | ≥ 20 mm Hg |
| Hemoglobin | < 8 gm/dL |
| International normalized ratio | > 1.4 |
| Platelets | <75 × 103/mm3 |
| Oxygen saturation | < 90% |
| Temperature | |
| Low | < 36.0°C (96.8°F) |
| High | > 38.3°C (101°F) |
| Brain tissue oxygen tension | < 15 mm Hg |
| Cerebral perfusion pressure | < 60 mm Hg |
| Pao2 | < 100 mm Hg |
| Glucose | |
| Low | < 80 mg/dL |
| High | >180 mg/dL |