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. 2021 Jan 1;12(3):771–789. doi: 10.7150/jca.49680

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MiR-1254 regulates the YAP-Hippo signaling pathway through PAX5. (A) Western blots of effects of overexpressing miR-1254 or PAX5 on protein levels of p-LATS1 and p-YAP in Hep3B cells. (B) Western blots of effects of knockdown of miR-1254 or PAX5 on protein levels of p-LATS1 and p-YAP in Huh-7 cells. (C) Immunofluorescence showed nuclear and cytoplasmic retention of YAP with overexpressed miR-1254 or PAX5 in Hep3B cells. (D) Immunofluorescence showed nuclear and cytoplasmic retention of YAP with knockdown of miR-1254 or PAX5 in Huh-7 cells. (scale bars: 20 µm). All data are means ± SD. **P<0.01.

MiR-1254 regulates the YAP-Hippo signaling pathway through PAX5. (A) Western blots of effects of overexpressing miR-1254 or PAX5 on protein levels of p-LATS1 and p-YAP in Hep3B cells. (B) Western blots of effects of knockdown of miR-1254 or PAX5 on protein levels of p-LATS1 and p-YAP in Huh-7 cells. (C) Immunofluorescence showed nuclear and cytoplasmic retention of YAP with overexpressed miR-1254 or PAX5 in Hep3B cells. (D) Immunofluorescence showed nuclear and cytoplasmic retention of YAP with knockdown of miR-1254 or PAX5 in Huh-7 cells. (scale bars: 20 µm). All data are means ± SD. **P<0.01.