Table 1.
Association between miR-1254 expression levels and clinicopathologic features in patients with hepatocellular carcinoma
| Characteristics | Number (n=50) | miR-1254 expression levels | P-value | |
|---|---|---|---|---|
| Low (n=19) | High (n=31) | |||
| Age (years) | 0.409 | |||
| ≤60 | 15 | 7 | 8 | |
| >60 | 35 | 12 | 23 | |
| Gender | 0.198 | |||
| Male | 37 | 16 | 21 | |
| Female | 13 | 3 | 10 | |
| HBV infection | 0.326 | |||
| Negative | 12 | 6 | 6 | |
| Positive | 38 | 13 | 25 | |
| Liver cirrhosis | 0.261 | |||
| Absent | 7 | 4 | 3 | |
| Present | 43 | 15 | 28 | |
| AFP (ng/ml) | 0.082 | |||
| ≤20 | 14 | 8 | 6 | |
| >20 | 36 | 11 | 25 | |
| Tumor size (cm) | 0.019* | |||
| ≤5 | 29 | 15 | 14 | |
| >5 | 21 | 4 | 17 | |
| Tumor multiplicity | 0.392 | |||
| Single | 36 | 15 | 21 | |
| Multiple | 14 | 4 | 10 | |
| Vascular invasion | 0.033* | |||
| No | 33 | 16 | 17 | |
| Yes | 17 | 3 | 14 | |
| Edmondson grade | 0.032* | |||
| I+II | 30 | 15 | 15 | |
| III+IV | 20 | 4 | 16 | |
HBV: hepatitis B virus AFP: alpha-fetoprotein;
*p < 0.05, statistically significant difference.