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Kinetic properties of CSF-1 and IL-34 binding to CSF-1R
| Proteins | Binding characteristic | KD | Kon | Koff |
|---|---|---|---|---|
| CSF-1/CSF-1R | hydrophilic | 1 pM | 6.29 × 107 s-1 M-1 | 6.55 × 10-5 s-1 |
| IL-34/CSF-1R | hydrophobic | 34 pM | 1.7 × 107 s-1 M-1 | 6.03 × 10-4 s-1 |
KD: equilibrium dissociation constant; Kon: association rate constant; Koff: dissociation rate constant. Data from 25.
