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. 2021 Jan 1;11(4):1703–1720. doi: 10.7150/thno.43895

Table 1.

Mitochondrial complex I proteins regulated by ginsenoside Rb1 during the early reperfusion stage

Protein ID Description Abbreviation MP Ratio p-value
I/R vs. S Rb1 vs. S Rb1 vs. I/R (Rb1 vs. S)-
(I/R vs. S)
I/R vs. S Rb1 vs. S Rb1 vs. I/R
Q91VD9 NADH-ubiquinone oxidoreductase 75 kDa subunit Ndufs1 29 1.093 0.965 0.883 -0.128 0.002 0.289 0.011
Q91WD5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2 Ndufs2 15 1.122 0.978 0.872 -0.144 0.008 0.432 0.005
Q9CXZ1 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 Ndufs4 7 1.131 0.993 0.878 -0.138 0.006 0.799 0.002
Q9DC70 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7 Ndufs7 7 1.087 0.999 0.919 -0.088 0.039 0.965 0.049
P52503 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6 Ndufs6 6 1.074 0.896 0.834 -0.178 0.022 0.005 0.000
Q91YT0 NADH dehydrogenase [ubiquinone] flavoprotein 1 Ndufv1 18 1.090 0.967 0.887 -0.123 0.009 0.336 0.012
Q9D6J6 NADH dehydrogenase [ubiquinone] flavoprotein 2 Ndufv2 11 1.075 0.949 0.883 -0.126 0.010 0.269 0.043
Q9CQ54 NADH dehydrogenase [ubiquinone] 1 subunit C2 Ndufc2 8 1.079 1.004 0.931 -0.075 0.020 0.843 0.014
Q9CR61 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 Ndufb7 9 1.113 0.909 0.817 -0.204 0.023 0.033 0.004
Q9CQJ8 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 Ndufb9 9 1.104 0.979 0.886 -0.125 0.019 0.437 0.005
Q3UIU2 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 Ndufb6 7 1.096 0.956 0.872 -0.140 0.030 0.333 0.024
Q9D6J5 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8 Ndufb8 5 1.125 0.981 0.873 -0.144 0.035 0.582 0.025
Q9CQH3 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5 Ndufb5 5 1.073 0.978 0.911 -0.095 0.007 0.569 0.047
Q9CQC7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 Ndufb4 5 1.114 1.024 0.919 -0.090 0.033 0.567 0.041
O09111 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11 Ndufb11 3 1.101 1.008 0.916 -0.093 0.026 0.856 0.048
Q99LC3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10 Ndufa10 17 1.086 0.964 0.888 -0.122 0.004 0.090 0.169
Q7TMF3 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 Ndufa12 14 1.103 1.024 0.928 -0.079 0.048 0.598 0.002
Q9ERS2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Ndufa13 9 1.088 0.982 0.903 -0.106 0.004 0.514 0.020
Q9CPP6 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 Ndufa5 7 1.093 1.033 0.945 -0.060 0.018 0.287 0.030
Q9CQ75 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 Ndufa2 6 1.096 0.990 0.903 -0.106 0.045 0.805 0.010

MP, matched peptides; S, sham group; I/R, ischemia/reperfusion group; Rb1, I/R plus ginsenoside Rb1 treated group.