Table 1.
Genome positions, protein sizes, and nucleotide and amino acid sequence identity values for different regions of the SMU-TP-YN18 genome and SMU-TP-GZ18 compared with bufavirus reference strains
| Region | Length (nt/aa) | Pairwise % identity (nt/aa) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Tibetan pig origin | Domestic pig origin1 | Human origin1 | Canine origin1 | Bat origin1 | Rat origin1 | ||||
| SMU-TP-YN18 | SMU-TP-GZ18 | FJNP2018 | Anhui021 | 61/Austria/2014 | BJ181 | CBuV-88 | MAG12-57 | SY-2015 | |
| Complete genome | 4189 | 4189 | 97.4* | 95.4* | 94.9* | 62.9* | 63.5* | 58.7* | 52.2* |
| 94.9** | 98.0** | 98.3** | 63.2** | 63.6** | 58.2** | 52.2** | |||
| NS1 | 1741/579 | 1741/579 | 98.7/97.4 | 98.4/96.0 | 97.3/92.8 | 44.4/36.3 | 59.4/37.8 | 57.1/37.6 | 57.3/36.3 |
| 97.3/93.8 | 98.2/95.6 | 99.2/96.0 | 44.8/34.2 | 60.2/38.4 | 57.4/37.5 | 57.4/36.3 | |||
| VP1 | 2035/679 | 2035/679 | 97.2/93.4 | 93.3/91.4 | 93.2/91.4 | 73.0/67.7 | 70.4/67.5 | 64.3/56.6 | 57.3/50.3 |
| 93.2/91.4 | 97.8/97.6 | 98.6/98.4 | 72.6/68.6 | 69.7/67.8 | 64.3/57.9 | 56.7/49.9 | |||
| SHP | 389/129 | 389/129 | 98.9/91.4 | 86.7/81.5 | 86.2/82.3 | – | – | – | – |
| 86.2/82.3 | 96.7/98.5 | 98.8/99.5 | – | – | – | – | |||
| VP2 | 1613/538 | 1613/538 | 95.6/93.4 | 92.6/83.9 | 92.3/84.2 | 72.6/53.5 | 69.0/46.6 | 63.6/43.5 | 56.0/34.3 |
| 92.6/84.2 | 97.7/94.3 | 99.2/97.6 | 72.0/51.8 | 68.0/44.7 | 63.0/42.3 | 55.4/34.3 | |||
1 In each box, the upper figure is the percentage identity to SMU-TP-YN18 (*) and the lower figure is the percentage identity to SMU-TP-GZ18 (**). The highest nucleotide and amino acid sequence identities of different regions are indicated in bold typeface. “–” indicates the lack of an SHP gene in bufavirus originating from humans, canines, bats, and rats.