Table 2.
Results of Reverse transcription-PCR SARS-CoV-2 testing and serology in children by pauci-symptomatic and asymptomatic groups
| Overall, N=605 | Pauci-symptomatic children,* n=283 | Asymptomatic children | |||
| Previously symptomatic (>7 days),† n=118 | No previous symptoms,§ n=204 | Total, n=322 | |||
| Reverse transcription-PCR | |||||
| Overall | 11 (1.8) (0.9 to 3.2) |
7 (2.5) (1.0 to 5.0) |
1 (0.8) (0.0 to 4.6) |
3 (1.5) (0.3 to 4.2) |
4 (1.2) (0.3 to 3.1) |
| Definitely positive‡ | 5 | 3 | 0 | 2 | 2 |
| Weakly positive¶ | 1 | 1 | 0 | 0 | 0 |
| Presumptive** | 5 | 3 | 1 | 1 | 2 |
| Serology | |||||
| IgM+ and/or IgG+ | 65 (10.7) (8.4 to 13.5) |
24 (8.5) (5.5 to 12.4) |
28 (23.7)‡ (16.4 to 32.4) |
13 (6.4)‡ (3.4 to 10.7) |
41 (12.7) (9.3 to 16.9) |
| IgM+IgG− | 7 (1.2) (0.5 to 2.4) |
4 (1.4) (0.4 to 3.6) |
2 (1.7) (0.2 to 6.0) |
1 (0.5) (0.0 to 2.7) |
3 (0.9) (0.2 to 2.7) |
| IgM+IgG+ | 32 (5.3) (3.6 to 7.4) |
12 (4.2) (2.2 to 7.3) |
17 (14.4)‡ (8.6 to 22.1) |
3 (1.5)‡ (0.3 to 4.2) |
20 (6.2) (3.8 to 9.4) |
| IgM−IgG+ | 26 (4.2) (2.8 to 6.2) |
8 (2.8) (1.2 to 5.5) |
9 (7.6) (3.5 to 14.0) |
9 (4.4) (2.0 to 8.2) |
18 (5.6) (3.3 to 8.7) |
Data are n (%) (95% CI).
*Pauci-symptomatic children were those with fever isolated or associated with respiratory signs such as cough, dysphagia, rhinorrhoea, diarrhoea, vomiting, rash, dysgeusia and/or anosmia, during the previous 7 days.
†Previously symptomatic (fever or respiratory or digestive) between 7 days and 2 months before enrolment.
‡Definitey positive: Ct value<38 obtained for two or three genes.
§No previous symptoms.
¶Weakly positive: any result with a Ct value of >38 and <40.
**Presumptive: Ct<38 obtained for only one target.
Ct, cycle threshold.