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. 2021 Jan 3;40(4):1233–1244. doi: 10.1007/s10067-020-05569-4

Table 1.

Definition of multisystem inflammatory syndrome in adults (MIS-A) [30]

Definition of multisystem inflammatory syndrome in adults (MIS-A)
1) A severe illness requiring hospitalisation in a person aged ≥ 21 years.
2) A positive test result for current or previous SARS-CoV-2 infection (nucleic acid, antigen, or antibody) during admission or in the previous 12 weeks.
3) Severe dysfunction of one or more extrapulmonary organ systems (e.g. hypotension or shock, cardiac dysfunction, arterial or venous thrombosis or thromboembolism, or acute liver injury).
4) Laboratory evidence of severe inflammation (e.g. elevated CRP, ferritin, D-dimer, or interleukin-6).
5) Absence of severe respiratory illness (to exclude patients in which inflammation and organ dysfunction might be attributable simply to tissue hypoxia).
- Patients with mild respiratory symptoms who met these criteria were included.
- Patients were excluded if alternative diagnoses such as bacterial sepsis were identified.