Table 1.
Definition of multisystem inflammatory syndrome in adults (MIS-A) [30]
Definition of multisystem inflammatory syndrome in adults (MIS-A) | |
1) A severe illness requiring hospitalisation in a person aged ≥ 21 years. | |
2) A positive test result for current or previous SARS-CoV-2 infection (nucleic acid, antigen, or antibody) during admission or in the previous 12 weeks. | |
3) Severe dysfunction of one or more extrapulmonary organ systems (e.g. hypotension or shock, cardiac dysfunction, arterial or venous thrombosis or thromboembolism, or acute liver injury). | |
4) Laboratory evidence of severe inflammation (e.g. elevated CRP, ferritin, D-dimer, or interleukin-6). | |
5) Absence of severe respiratory illness (to exclude patients in which inflammation and organ dysfunction might be attributable simply to tissue hypoxia). | |
- Patients with mild respiratory symptoms who met these criteria were included. | |
- Patients were excluded if alternative diagnoses such as bacterial sepsis were identified. |