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. 2020 Oct 29;49(D1):D751–D763. doi: 10.1093/nar/gkaa939

Table 2.

Pfams with statistically significant differences between butyrivibrio_bin_group and two groups of isolate Butyrivibrio and Pseudobutyrivibrio genomes. Adjusted P-value is Kruskal-Wallis test P-value with FDR controlled at 1% using Benjamini-Hochberg method

Pfam ID Pfam definition Pfam functional category Mean count, butyrivibrio_bin_group (n = 10) Mean count enolase_positive_group (n = 46) Mean count, enolase_negative_group (n = 32) Adjusted P-value
PF03418 Germination protease Sporulation 1 0.021739 0 6.91E-16
PF03419 Sporulation factor SpoIIGA Sporulation 1 0.021739 0 6.91E-16
PF05580 SpoIVB peptidase S55 Sporulation 1 0.021739 0 6.91E-16
PF06686 Stage III sporulation protein AC/AD protein family Sporulation 2 0.043478 0 6.91E-16
PF06898 Putative stage IV sporulation protein YqfD Sporulation 1.1 0.021739 0 6.91E-16
PF07451 Stage V sporulation protein AD (SpoVAD) Sporulation 1 0.021739 0 6.91E-16
PF07454 Stage II sporulation protein P (SpoIIP) Sporulation 1 0.021739 0 6.91E-16
PF09547 Stage IV sporulation protein A (spore_IV_A) Sporulation 1.1 0.021739 0 6.91E-16
PF09548 Stage III sporulation protein AB (spore_III_AB) Sporulation 1 0.021739 0 6.91E-16
PF09551 Stage II sporulation protein R (spore_II_R) Sporulation 1.2 0.021739 0 6.91E-16
PF09578 Spore cortex protein YabQ (Spore_YabQ) Sporulation 1 0.021739 0 6.91E-16
PF12116 Stage III sporulation protein D Sporulation 1 0.021739 0 6.91E-16
PF12685 SpoIIIAH-like protein Sporulation 1 0.021739 0 6.91E-16
PF03862 SpoVA protein Sporulation 2 0.043478 0 7.68E-16
PF08486 Stage II sporulation protein Sporulation 1.9 0.043478 0 7.68E-16
PF08769 Sporulation initiation factor Spo0A C terminal Sporulation 1.8 0.043478 0 8.61E-16
PF03323 Bacillus/Clostridium GerA spore germination protein Sporulation 0.9 0.021739 0 4.69E-14
PF09581 Stage III sporulation protein AF (Spore_III_AF) Sporulation 1 0.021739 0 4.69E-14
PF11007 Spore coat associated protein JA (CotJA) Sporulation 0.9 0.021739 0 4.69E-14
PF12652 CotJB protein Sporulation 0.9 0.021739 0 4.69E-14
PF15714 Stage V sporulation protein T C-terminal, transcription factor Sporulation 0.9 0.021739 0 4.69E-14
PF12164 Stage V sporulation protein AA Sporulation 0.8 0.021739 0 4.20E-12
PF13782 Stage V sporulation protein AB Sporulation 0.8 0.021739 0 4.20E-12
PF00269 Small, acid-soluble spore proteins, alpha/beta type Sporulation 0.7 0.021739 0 3.13E-10
PF02654 Cobalamin-5-phosphate synthase Cobalamin biosynthesis 0 0.978261 0.90625 3.48E-12
PF07685 CobB/CobQ-like glutamine amidotransferase domain Cobalamin biosynthesis 0 1.913043 1.75 6.14E-10
PF01890 Cobalamin synthesis G C-terminus Cobalamin biosynthesis 0 0.934783 0.84375 4.67E-09
PF02570 Precorrin-8X methylmutase Cobalamin biosynthesis 0 0.934783 0.84375 4.67E-09
PF02571 Precorrin-6x reductase CbiJ/CobK Cobalamin biosynthesis 0 0.934783 0.84375 4.67E-09
PF06180 Cobalt chelatase (CbiK) Cobalamin biosynthesis 0 0.934783 0.84375 4.67E-09
PF11760 Cobalamin synthesis G N-terminal Cobalamin biosynthesis 0 0.934783 0.84375 4.67E-09