Table 1.
Detailed data content of MarkerDB (Version 1.0)
| Biomarker data in MarkerDB | Total |
|---|---|
| Total number of biomarkers | 27 759 |
| Number of clinically approved biomarkers | 26 493 |
| Number of pre-clinical or investigational biomarkers | 1226 |
| Number of singular biomarkers (one marker – one condition) | 26 628 |
| Number of biomarkers in multi-marker panels | 1219 |
| Number of multi-marker panels | 451 |
| Number of chemical biomarkers | 1089 |
| Number of protein biomarkers | 142 |
| Number of DNA mutation biomarkers | 26 021 |
| Number of DNA SNP biomarkers | 353 |
| Number of viral/bacterial DNA biomarkers | 23 |
| Number of karyotype biomarkers | 154 |
| Number of diagnostic biomarkers | 25 560 |
| Number of prognostic biomarkers | 102 |
| Number of predictive biomarkers | 6746 |
| Number of Exposure (diet and chemical) biomarkers | 265 |
| Number of diet-related biomarkers | 49 |
| Number of diseases/conditions with biomarkers | 699 |
| Average number of biomarkers per disease | 41 |
| Percentage of chemical biomarkers with ROC or cut-off data | 98% |
| Percentage of protein biomarkers with ROC or cut-off data | 29% |
| Percentage of DNA biomarkers with ROC or cut-off data | >90% |
| Number of chemicals with structures | 978 |
| Number of proteins with 3D structures/PDB links | 121 |
| Number of protein sequences | 142 |
| Number of DNA sequences | 26 374 |
| Average number of words in disease descriptions | 147 |
| Average number of words in chemical descriptions | 214 |
| Average number of words in protein descriptions | 176 |
| Average number of words in gene descriptions | 89 |
| Number of references (PubMed IDs or DOIs) | 5391 |