Table 1.
Online bioinformatics tools for Acr research
| Name (ref.) | Year | Resource provided | Features |
|---|---|---|---|
| Anti-CRISPRDB (19) | 2018 | Database | Experimentally characterized Acrs and their homologs and BLAST search |
| CRISPRminer (20) | 2018 | Database | Experimentally characterized Acrs and their homologs and genomic context |
| Acr nomenclature (14) | 2018 | Google spreadsheets | Experimentally characterized Acrs and Acas nomenclature |
| Self-Targeting Spacer Searcher (27) | 2018 | Standalone package | Workflow for self-targeting spacer identification |
| AcrCatalog (21) | 2020 | Database and model code | Predicted Acrs from decision tree ML classifier + heuristic filtering |
| AcRanker (23) | 2020 | Web server and standalone package | XGBoost classifier using AA biases |
| AcrFinder (22) | 2020 | Web server and standalone package | Workflow combining Homology + GBA + self-targeting and user-friendly website |
| PaCRISPR (24) | 2020 | Web server | SVM classifier using PSSMs to capture evolutionary features |
| AcrDetector (29) | 2020 | Model code | Decision tree classifier using six sequence features |