Table 1.
Software programs integrated into MobiDB 4. Pfam and Gene3D (*) annotations are retrieved from the InterPro database, all other software are executed locally in the MobiDB server
| Method | Input | Features | Reference |
|---|---|---|---|
| Mobi | Structure | Binding modes, missing residues, mobile residues, high temperature residues | (43) |
| FLIPPER | Structure | Linear interacting peptides | Unpublished |
| RING | Structure | Residue Interaction Network | (40) |
| MobiDB-lite | Sequence | Disorder, cysteine rich, proline rich, polar, negative polyelectrolyte, positive polyelectrolyte, polyampholyte | (32) |
| ESpritz-DisProt | Sequence | Disorder | (54) |
| ESpritz-NMR | Sequence | Disorder | (54) |
| ESpritz-Xray | Sequence | Disorder | (54) |
| IUPred-Long | Sequence | Disorder | (55) |
| IUPred-Sort | Sequence | Disorder | (55) |
| VSL2b | Sequence | Disorder | (56) |
| DisEMBL-465 | Sequence | Disorder | (57) |
| DisEMBL-HotLoops | Sequence | Disorder | (57) |
| GlobPlot | Sequence | Disorder | (58) |
| JRONN | Sequence | Disorder | (59) |
| ANCHOR | Sequence | Linear interacting peptides | (42) |
| FeSS | Sequence | Secondary structure | (60) |
| DynaMine | Sequence | Backbone rigidity | (61) |
| Pfilt | Sequence | Low complexity | (62) |
| SEG | Sequence | Low complexity | (63) |
| Gene3D (*) | Sequence | Conserved domains | (64) |
| Pfam (*) | Sequence | Conserved domains | (65) |