Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 21;49(D1):D998–D1003. doi: 10.1093/nar/gkaa884

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Figure 1. — Statistics on 581 human cell lines collected in OGEE v3. (A) The 581 cell lines were related to 25 different tissues by their histological origins. (B) CRISPR-based method often identified more essential genes than RNAi-based method. Each point indicates a cell line, and the x-axis and y-axis mean the number of identified essential genes of the cell line in CRISPR–Cas9 and RNAi datasets respectively. The colors (blue, green, red, yellow) illustrate the number of overlapping essential genes between CRISPR–Cas9 and RNAi data. The red line denotes the fitted regression line between numbers of essential genes in RNAi and CRISPR-Cas9 data. In total 150 cell lines were tested by both techniques.