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Time courses of serum vitamin D3 concentration (A) and serum 25(OH)D3 concentration (B) in the placebo and vitamin D3 (2000 IU/d) groups in pilot study 1. Data are means ± SDs; n = 11/group, 104 observations total, and 6 missing observations (2 at month 1, 1 at month 6, and 3 at month 12). SI conversion factors: vitamin D3, 1 ng/mL = 2.6 nmol/L; 25(OH)D3, 1 ng/mL = 2.5 nmol/L. BL, baseline; 25(OH)D3, 25-hydroxyvitamin D3.
