Serum and SUBQ adipose tissue concentrations of vitamin D3 and 25(OH)D3 at baseline (open circles) and after 3 mo of supplementation (closed circles) with 2000 IU/d (n = 8) or 4000 IU/d (n = 7) of vitamin D3 in pilot study 2. For each visit separately, bivariate associations were estimated with r when both variables were normally distributed or rs when ≥1 variable was skewed. (A) Adipose tissue 25(OH)D3 compared with adipose tissue vitamin D3; (B) adipose tissue vitamin D3 compared with serum vitamin D3; (C) adipose tissue 25(OH)D3 compared with serum 25(OH)D3; (D) adipose tissue vitamin D3 compared with serum 25(OH)D3; (E) adipose tissue 25(OH)D3 compared with serum vitamin D3; (F) serum 25(OH)D3 compared with serum vitamin D3. SI conversion factors: vitamin D3, 1 ng/mL = 2.6 nmol/L, 1 pg/mg = 2.6 nmol/kg; 25(OH)D3, 1 ng/mL = 2.5 nmol/L, 1 pg/mg = 2.5 nmol/kg. BL, baseline; SUBQ, subcutaneous; 25(OH)D3, 25-hydroxyvitamin D3.