FIGURE 3.

Global cognitive function by tertile of plasma folate, among 1408 Boston Puerto Rican Health Study participants at baseline. Adjusted for age (y), sex (premenopausal or postmenopausal female with estrogen use, female postmenopausal with no estrogen use, or male), BMI (in kg/m²), physical activity score, diabetes (yes/no), education level (≤8^th grade, 9^th–12^th grade, or college), smoking (past, current, or none), alcohol use (heavy, none, or moderate), apoE ε4 carrier (yes/no), vitamin B-6 (pyridoxal-5-phosphate; nmol/L), and vitamin B-12 (pmol/L). *Significantly different from tertile 1 (P = 0.05).