Table 3.
Change in measures of glycemic variability
| Baseline (days 1–15) |
Final phase (days 76–90) |
Change |
95% CI for change |
P‐value | |
|---|---|---|---|---|---|
| SD glucose (mg/dL) | 57 ± 16 | 52 ± 14 | −5 ± 9 | (−7, −3) | <0.0001 |
| CV glucose (%) | 33.8 ± 7.4 | 33.0 ± 6.8 | −0.8 ± 4.4 | (−1.7, 0.1) | 0.0774 |
| LBGI | 0.58 ± 0.73 | 0.62 ± 0.59 | 0.04 ± 0.69 | (−0.11, 0.18) | 0.6267 |
| HBGI | 8.3 ± 4.3 | 6.5 ± 3.8 | −1.8 ± 3.6 | (−2.5, −1.0) | <0.0001 |
| BGRI | 8.9 ± 4.1 | 7.1 ± 3.7 | −1.8 ± 3.2 | (−2.4, −1.1) | <0.0001 |
| CONGA 1 h (mg/dL) | 38.8 ± 9.0 | 36.2 ± 8.5 | −2.6 ± 4.8 | (−3.5, −1.6) | <0.0001 |
| CONGA 2 h (mg/dL) | 58.4 ± 14.1 | 54.1 ± 13.3 | −4.4 ± 8.0 | (−6.0, −2.7) | <0.0001 |
| CONGA 4 h (mg/dL) | 76.1 ± 19.1 | 69.3 ± 18.2 | −6.8 ± 11.6 | (−9.2, −4.4) | <0.0001 |
| CONGA 6 h (mg/dL) | 79.7 ± 21.8 | 72.3 ± 20.2 | −7.4 ± 13.7 | (−10.2, −4.5) | <0.0001 |
| MODD (mg/dL) | 51.1 ± 15.4 | 47.1 ± 13.5 | −4.1 ± 10.1 | (−6.2, −2.0) | 0.0002 |
| SD rate of change (mg/dL/min) | 0.86 ± 0.19 | 0.81 ± 0.18 | −0.05 ± 0.09 | (−0.07, −0.03) | <0.0001 |
Total n = 92. Data presented as the mean ± standard deviation.
BGRI, blood glucose risk index; CI, confidence interval; CONGA, continuous overall net glycemic action; CV, coefficient of variation; HBGI, high blood glucose index; LBGI, low blood glucose index; MODD, mean of daily differences; SD, standard deviation.