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. 2021 Jan 4;9:3. doi: 10.1186/s40345-020-00207-z

Table 1.

Main large samples (> 1000 patients) studies on Bipolar Disorder published in the last ten years

Authors Site Sample N° of BD patients recruited Female patients (%)
Bareis et al. 2018 U.S.A. STEP-BD (1999-2005) 3563 57,65%
Bobo et al. 2018 U.S.A. Mayo Clinic Biobank (started in 2009)

1465

BD-I = 69,42%

BD-II = 30,58%

60,75%

BD-I = 58,60%

BD-II = 66,10%

Buoli et al. 2019 Italy RENDiBi Study (April 2014-March 2015)

1675

BD-I = 62,21%

BD-II = 37,79%

57,40%
Crump et al. 2013 Sweden National Registry (2001-2002) 6618 59,20%
Hayes et al. 2017 U.K. Primary care electronics health records (THIN) (2000-2014) 17341 58,83%
Hou et al. 2016 Australia, Canada, Czech Republic, France, Germany, Italy, Japan, Poland, Romania,Spain, Sweden, Switzerland, Taiwan, U.S.A. ConLiGen 2563 57,63%
Kalman et al. 2019 Austria, Australia, Canada, Czech Republic, France, Germany, Italy, Poland, Romania, Spain, Sweden, U.S.A. ConLiGen, Bonn-Mannheim and PsyCourse 1995 (BD-I patients only) 55,10%
Karanti et al. 2015 Sweden Swedish National Quality Assurance Register for Bipolar Disorder (BipoläR) (2004-2011)

7136

BD-I = 47,09%

BD-II = 38,15%

BD-NOS = 14,76%

61,27%

BD-I = 57,30%

BD-II = 64,95%

BD-NOS = 64,42%

Vieta et al. 2013 Austria, Belgium, Brazil, France, Germany, Portugal, Romania, Turkey, Ukraine, Venezuela WAVE-BD (April 2010- June 2011)

2896

BD-I = 68,70%

BD-II = 31,3%

65,00%
Yoon et al. 2018 Korea Korean HIRA-NPS (2013 sample only) 2626 58,80%

THIN = The Health Improvement Network; STEP-BD = Systematic Treatment Enhancement Program for Bipolar Disorder; RENDiBi = National Epidemiological Research on Bipolar Disorder; HIRA-NPS = Health Insurance Review and Assessment Service – National Patient Sample; WAVE-BD = Wide Ambispective of Bipolar Disorder; ConLiGen = The International Consortium on Lithium Genetics; BD-I = Bipolar Disorder type I