Table 1.
Test-retest reliability statistics for microstructure measures. Units (mean and SD) for MD and RD = 10−3 mm2/s; units for R1 = s−1, CV = averaged within subject, ICC = averaged across 5 repeated measures.
Metric | Tract | Mean | SD | CV (%) | ICC | ICC pval | r |
---|---|---|---|---|---|---|---|
FA | 0.47 | 0.005 | 1.0 | 0.93 | <0.0001 | 0.82 | |
MD | 1.00 | 0.010 | 0.9 | 0.94 | <0.0001 | 0.87 | |
RD | 1.00 | 0.004 | 0.6 | 0.96 | <0.0001 | 0.88 | |
RSF | 0.13 | 0.003 | 2.1 | 0.88 | <0.0001 | 0.65 | |
MMPF | Fornix | 0.05 | 0.001 | 2.6 | 0.95 | <0.0001 | 0.85 |
MWF | 0.07 | 0.003 | 4.2 | 0.95 | <0.0001 | 0.87 | |
R1 | 0.77 | 0.005 | 0.7 | 0.97 | <0.0001 | 0.90 | |
MTR | 0.35 | 0.0004 | 0.1 | 0.94 | <0.0001 | 0.77 | |
FA | 0.55 | 0.003 | 0.6 | 0.97 | <0.0001 | 0.89 | |
MD | 0.41 | 0.002 | 0.5 | 0.95 | <0.0001 | 0.81 | |
RD | 0.63 | 0.001 | 0.2 | 0.95 | <0.0001 | 0.78 | |
RSF | 0.27 | 0.003 | 1.2 | 0.86 | 0.002 | 0.52 | |
MMPF | CST | 0.09 | 0.001 | 1.5 | 0.97 | 0.0003 | 0.74 |
MWF | 0.16 | 0.003 | 1.7 | 0.97 | <0.0001 | 0.95 | |
R1 | 1.04 | 0.004 | 0.4 | 0.98 | <0.0001 | 0.91 | |
MTR | 0.41 | 0.002 | 0.5 | 0.78 | 0.01 | 0.37 | |
FA | 0.47 | 0.005 | 1.0 | 0.95 | <0.0001 | 0.86 | |
MD | 0.47 | 0.005 | 1.0 | 0.96 | <0.0001 | 0.85 | |
RD | 0.64 | 0.003 | 0.5 | 0.96 | <0.0001 | 0.81 | |
RSF | Arcuate Fasciculus | 0.26 | 0.004 | 1.7 | 0.82 | 0.005 | 0.72 |
MMPF | 0.10 | 0.002 | 2.1 | 0.92 | <0.0001 | 0.79 | |
MWF | 0.16 | 0.002 | 1.4 | 0.98 | <0.0001 | 0.93 | |
R1 | 1.07 | 0.001 | 0.1 | 0.97 | <0.0001 | 0.90 | |
MTR | 0.42 | 0.003 | 0.6 | 0.97 | <0.0001 | 0.92 |
One-way ANOVAs demonstrated no significant differences between ICC computed for individual time point pairs or between average ICC and individual time point ICC comparisons for the CST (F(9,70) = 0.74, p = .67) and the Fornix (F(9,70) = 0.19, p = .07). Although initially a difference was suggested for the Arcuate Fasciculus (F(9,70) = 2.2, p = .03), no comparisons survived correction for multiple comparisons as shown with Tukey post-hoc correction.