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ROC Curve Analysis of ANXA4 and AFP for Prediction of HCC in Cirrhotic Patients
| Variable | Optimal cutoff | AUC | Sensitivity | Specificity | PPV | NPV | Accuracy |
|---|---|---|---|---|---|---|---|
| ANXA4 (ng/ml) | ≥ 115 | 0.972 | 95% | 80% | 93% | 94% | 93.50% |
| AFP (ng/ml) | ≥ 200 | 0.842 | 78% | 90% | 95% | 58% | 81.50% |
| ANXA4 & AFP | 98% | 88% | 92% | 93% | 93% | ||
ANXA4, Annexin A4; AFP, alpha-fetoprotein; AUC, area under the curve; PPV, positive predictive value; NPV, negative predictive value
