Table 2.
Clinicopathological Data in Relation to the Diagnosis (n=57)
| Variables | Diagnosis | P value | ||
|---|---|---|---|---|
| Benign | Borderline | Malignant | ||
| n (%) | n (%) | n (%) | ||
| Clinical Data | ||||
| Age | >0.950 | |||
| Less than 20 | 3 (100.0) | 0 (0.0) | 0 (0.0) | |
| More than 20 | 39 (72.2) | 9 (16.7) | 6 (11.1) | |
| Race | >0.950 | |||
| Malay | 41 (73.2) | 9 (16.1) | 6 (10.7) | |
| Chinese | 1 (00.0) | 0 (0.0) | 0 (0.0) | |
| Treatment | <0.001 | |||
| Defaulted | 6 (85.7) | 1 (14.3) | 0 (0.0) | |
| Lumpectomy | 27 (93.1) | 2 (6.9) | 0 (0.0) | |
| Mastectomy | 3 (25.0) | 4 (33.3) | 5 (41.7) | |
| WLE | 6 (66.7) | 2 (22.2) | 1 (11.1) | |
| Skin changes | 0.004 | |||
| No | 38 (80.9) | 7 (14.9) | 2 (4.3) | |
| Yes | 4 (40.0) | 2 (20.0) | 4 (40.0) | |
| Lump size | 0.052 | |||
| Less 3 cm | 24 (88.9) | 2 (7.4) | 1 (3.7) | |
| More 3 cm | 18 (60.0) | 7 (23.3) | 5 (16.7) | |
| Histopathological examination (HPE) | ||||
| Atypia | <0.001 | |||
| Yes | 4 (22.2) | 8 (44.4) | 6 (33.3) | |
| No | 38 (97.4) | 1 (2.6) | 0 (0.0) | |
| Stromal hypercellularity | 0.012 | |||
| No | 26 (86.7) | 4 (13.3) | 0 (0.0) | |
| Yes | 16 (59.3) | 5 (18.5) | 6 (22.2) | |
| Stromal overgrowth | 0.33 | |||
| No | 12 (92.3) | 1 (7.7) | 0 (0.0) | |
| Yes | 30 (68.2) | 8 (18.2) | 6 (13.6) | |
| Mitosis | <0.001 | |||
| <5 | 42 (93.3) | 3 (6.7) | 0 (0.0) | |
| 5-9 | 0 (0.0) | 6 (85.7) | 1 (14.3) | |
| >9 | 0 (0.0) | 0 (0.0) | 5 (100.0) | |
| Immunohistochemistry (IHC) | ||||
| Ki67 | <0.001 | |||
| Negative/mild | 42 (82.4) | 9 (17.6) | 0 (0.0) | |
| Mod | 0 (0.0) | 0 (0.0) | 2 (100.0) | |
| Mark | 0 (0.0) | 0 (0.0) | 4 (100.0) | |
| p53 | <0.001 | |||
| Negative/mild | 32 (94.1) | 2 (5.9) | 0 (0.0) | |
| Mod | 10 (58.8) | 4 (23.5) | 3 (17.6) | |
| Mark | 0 (0.0) | 3 (50.0) | 3 (50.0) | |