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. 2020 Sep;21(9):2653–2659. doi: 10.31557/APJCP.2020.21.9.2653

Table 2.

Clinicopathological Data in Relation to the Diagnosis (n=57)

Variables Diagnosis P value
Benign Borderline Malignant
n (%) n (%) n (%)
Clinical Data
Age >0.950
Less than 20 3 (100.0) 0 (0.0) 0 (0.0)
More than 20 39 (72.2) 9 (16.7) 6 (11.1)
Race >0.950
Malay 41 (73.2) 9 (16.1) 6 (10.7)
Chinese 1 (00.0) 0 (0.0) 0 (0.0)
Treatment <0.001
Defaulted 6 (85.7) 1 (14.3) 0 (0.0)
Lumpectomy 27 (93.1) 2 (6.9) 0 (0.0)
Mastectomy 3 (25.0) 4 (33.3) 5 (41.7)
WLE 6 (66.7) 2 (22.2) 1 (11.1)
Skin changes 0.004
No 38 (80.9) 7 (14.9) 2 (4.3)
Yes 4 (40.0) 2 (20.0) 4 (40.0)
Lump size 0.052
Less 3 cm 24 (88.9) 2 (7.4) 1 (3.7)
More 3 cm 18 (60.0) 7 (23.3) 5 (16.7)
Histopathological examination (HPE)
Atypia <0.001
Yes 4 (22.2) 8 (44.4) 6 (33.3)
No 38 (97.4) 1 (2.6) 0 (0.0)
Stromal hypercellularity 0.012
No 26 (86.7) 4 (13.3) 0 (0.0)
Yes 16 (59.3) 5 (18.5) 6 (22.2)
Stromal overgrowth 0.33
No 12 (92.3) 1 (7.7) 0 (0.0)
Yes 30 (68.2) 8 (18.2) 6 (13.6)
Mitosis <0.001
<5 42 (93.3) 3 (6.7) 0 (0.0)
5-9 0 (0.0) 6 (85.7) 1 (14.3)
>9 0 (0.0) 0 (0.0) 5 (100.0)
Immunohistochemistry (IHC)
Ki67 <0.001
Negative/mild 42 (82.4) 9 (17.6) 0 (0.0)
Mod 0 (0.0) 0 (0.0) 2 (100.0)
Mark 0 (0.0) 0 (0.0) 4 (100.0)
p53 <0.001
Negative/mild 32 (94.1) 2 (5.9) 0 (0.0)
Mod 10 (58.8) 4 (23.5) 3 (17.6)
Mark 0 (0.0) 3 (50.0) 3 (50.0)