Table 3.
FOXE1 Genotypic and Allelic Frequency in TC Patients (n=81) and Healthy (n=165) Objects
| Gene | Accession number | Chromosome location | Genotype | Case N (%) N = 81 | Control N (%) N = 165 | p-value | OR |
|---|---|---|---|---|---|---|---|
| GG | 26 (32.1) | 66 (40.0) | Ref:1 | ||||
| AG | 40 (49.4) | 84 (50.9) | 0.52 | 1.2 | |||
| FOXE1 | rs1867277 | 9q22.33 | AA | 15 (18.5) | 15 (9.1) | 0.03* | 2.53 |
| AG+AA | 55 (67.9) | 99 (60.0) | 0.23 | 1.41 | |||
| Allele G | 92 (56.8) | 216 (65.5) | Ref:1 | ||||
| Allele A | 70 (43.2) | 114 (34.5) | 0.06 | 1.44 |
*, Significant values in bold. FOXE1 genotypes (GG, wild type; AG, heterozygote; AA, mutant type).