Figure 1.

Immunostaining for CD133 in the OED and OSCC Samples Analyzed. A, B and C, respectively, show cases of mild, moderate and severe dysplasia. A: Mild dysplasia showing CD133 positive cells in the cytoplasm with rare nuclear immunostaining (Magnification 400x). B: Moderate dysplasia showing both types of immunostaining (cytoplasmic and nuclear) (Magnification 400x). C: Severe dyspasia showing greater number and intensity of cellular immunostaining for CD133 in relation to the other degrees of dysplasia (both cytoplasmic and nuclear immunostaining are observed) (Magnification 400x). D: Example of immunostaining in OSCC. Note that the immunostaining intensity and number of CD133+ cells is greater than in cases of dysplasia. There is a predominance of nuclear immunostaining when compared to cases of dysplasia (Magnification 400x)