Figure 1.

Behavioral seizure expression in Wistar Audiogenic Rats (WAR). (A) Evolution of audiogenic seizures in animals submitted to chronic audiogenic seizures in the audiogenic kindling (AuK) protocol (n = 10). The Categorized Severity Index (Rossetti et al., 2006) was used to analyze brainstem seizures, while the Racine's scale (Racine, 1972) was used to analyze limbic seizures. It is possible to observe the presence of brainstem tonic-clonic seizures (white circles) in the beginning of the protocol and the development of limbic seizures (black circles) during the chronic phase of the protocol. (B) Mean of brainstem seizure severity in WARs submitted to a single acoustic stimulation (n = 5). Data are expressed as mean ± standard error mean (SEM).