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. 2020 Dec 28;27:77–89. doi: 10.1016/j.jot.2020.10.004

Fig. 8.

Fig. 8

(A) Differentially expressed proteins mapped to GO categories (biological processes and molecular function) (B) KEGG and PPI networks analysis of differentially expressed proteins between the control and experimental groups. The top 20 ranking of KEGG pathways and the PPI networks analysis.(C) Protein–protein interaction (PPI) network analysis of DEPs and osteoblast-associated proteins. Nodes represent proteins in the PPI network, and lines show the interaction among proteins. Protein–protein interaction (PPI) network analysis of DEPs and bone calcification-associated proteins. Nodes represent proteins in the PPI network, and lines show the interaction among proteins. The size and color of nodes are associated with the significance of proteins, while the thickness of lines is proportional to the strength of interactions among proteins.