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. 2020 Dec 21;8:618733. doi: 10.3389/fcell.2020.618733

FIGURE 2.

FIGURE 2

The interplay and interactions between biomolecular condensates and the cytoskeleton. (A) The transport of RNP transport granules (i), P-bodies (ii) and stress granules (iii) is mediated by the actin and microtubule cytoskeleton driven by motor proteins. (B) The formation/assembly, disassembly and the fusion/docking of P-bodies (i) and stress granules (ii) is influenced by the cytoskeleton and motor proteins. (C) The local cytoskeleton can be remodeled by RNPs through mRNA supply and local translation of both actin (i) and microtubule (ii) proteins. (D) Both actin (i) and microtubule (ii) nucleation can be driven by concentration of specific proteins via phase separation at specific sub-cellular locations.