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. 2020 Dec 21;14:575459. doi: 10.3389/fnins.2020.575459

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Copyright © 2020 Noonong, Sobhon, Sroyraya and Chaithirayanon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Dopaminergic neurons and fibers were detected with tyrosine hydroxylase (TH) immunostaining in the substantia nigra pars compacta (SNpc) and striatum of mice brain at high magnification (20 ×) containing immunolabeled TH-positive dopamine (DA) neurons and fibers (brown). (B) Number of dopaminergic neurons with TH immunostaining in SNpc on days 0 and 3. (C) Number of dopaminergic fibers with TH immunostaining in the striatum. Data are presented as the means ± standard error of the mean (SEM) *P < 0.05, **P < 0.01, and ***P < 0.001, in comparison with the NSS-injected group. ^##P < 0.01, and ^###P < 0.001, in comparison with the MPTP-injected group.