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. 2020 Dec 21;14:587747. doi: 10.3389/fncel.2020.587747

Figure 9.

Figure 9

CDK5 inhibition enhanced the effect of miR-125b inhibition on cell apoptosis and neurite outgrowth. Comparisons of CDK5 expression (A,B), cell apoptosis (C,D), and neurite outgrowth (E,F) among blank, NC, inhibitor-miR, Si-CDK5, and inhibitor-miRandSi-CDK5 cells in primary neuron AD model. Comparisons of CDK5 expression (G,H), cell apoptosis (I,J), and neurite outgrowth (K,L) among blank, NC, inhibitor-miR, Si-CDK5, and inhibitor-miRandSi-CDK5 cells in PC-12 cellular AD model. MiR-125b, microRNA-125b; CDK5, cyclin-dependent kinase 5; NC, negative control; AD, Alzheimer disease. *p < 0.05, **p < 0.01, ***p < 0.001.