. Author manuscript; available in PMC: 2022 Sep 1.

Published in final edited form as: Clin Gastroenterol Hepatol. 2020 Jul 4;19(9):1824–1834.e2. doi: 10.1016/j.cgh.2020.06.068

Table 4.

Multivariable adjusted case control odds ratios with 95% confidence limits for 206 eosinophilic esophagitis diagnoses per AGREE criteria among 221 subjects with overall peak eosinophil count greater or equal to 15 per high-power field.

	Case control odds ratio (95% confidence limits)

Clinical predictors and peak overall eosinophil count

Age at biopsy (per year)	0.94 (0.90 – 0.99)
Dysphagia at baseline	15.7 (2.5 – 96.8)
Higher peak overall eosinophil count (per hpf)	1.03 (1.01 – 1.06)

Clinical and endoscopic predictors and eosinophils

Rings, furrows, edema, white plaques, narrowing, or crepe paper appearance on endoscopy	3.9 (1.1 – 13.3)
Erythema	0.1 (0.0 – 1.1)
Hiatus hernia	0.1 (0.0 – 0.4)
Higher peak overall eosinophil count (per hpf)	1.03 (1.01 – 1.06)

All clinical, endoscopic, and histology predictors

Hiatus hernia	0.16 (0.04 – 0.61)
Eosinophil degranulation	0.07 (0.01 – 0.63)
Spongiosis	6.1 (1.4 – 26.3)
Higher peak overall eosinophil count (per hpf)	1.03 (1.00 – 1.05)

AGREE, A Working Group on Proton-pump Inhibitor Responsive Esophageal Eosinophilia, HPF, high-power field.