Figure 7.

Effects of Ccr2 or Ccr5 deficiency on myeloid and lymphoid blood cells in NEMO^LPC-KO mice. NEMO^WT, NEMO^LPC-KO, NEMO^LPC-KOCcr2^–/–, and NEMO^LPC-KOCcr5^–/– mice at the age of 8 weeks were analyzed for immune cell subsets in blood using flow cytometry. (A) Representative flow cytometric plots, (B) histograms of Ly6C expression on blood monocytes, and (C) statistical summary of cell frequencies. (D) Representative flow cytometric plots of lymphoid blood cells, and (E) statistical summary of cell frequencies. Data represent median of n = 4–14 ± SD; ∗P < .05, ∗∗∗P < .001 (1-way analysis of variance).