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. 2020 Dec 21;11:584374. doi: 10.3389/fneur.2020.584374

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Copyright © 2020 Lang, Gan, Yoon, Hanganu, Kibreab, Cheetham, Hammer, Kathol, Sarna, Martino and Monchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results from the functional connectivity analysis. (A) A significant decrease in connectivity between the stimulation site and the ipsilateral caudate head in the real stimulation group vs. the sham group as revealed by a significant condition*time interaction. Stimulation site did not change connectivity with any of the other striatal subregions assessed. (B) ROI–whole brain analysis revealed significantly decreased connectivity between the anterior putamen and the right medial orbitofrontal cortex. (C) Baseline connectivity between the stimulation network and the striatal network is related to change in executive functioning (EF) at 1 month in the real stimulation group.