Table 2. Performance of iodine-related parameters in diagnosing malignant and benign pulmonary.
| AUC (95% CI) | Cutoff | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | |
|---|---|---|---|---|---|---|---|
| CT40keV | |||||||
| AP | 0.82 (0.75–0.88) | 121.30 | 91.40 | 69.05 | 86.73 | 78.38 | 84.44 |
| VP | 0.89 (0.83–0.94) | 141.00 | 94.62 | 73.81 | 88.89 | 86.11 | 88.15 |
| λHU | |||||||
| AP | 0.77 (0.69–0.84) | 1.39 | 90.32 | 61.90 | 84.00 | 74.29 | 81.48 |
| VP | 0.89 (0.83–0.94) | 1.83 | 92.47 | 69.05 | 86.87 | 80.56 | 85.19 |
| NIC | |||||||
| AP | 0.87 (0.80–0.92) | 0.13 | 78.49 | 80.95 | 90.12 | 62.96 | 78.10 |
| VP | 0.93 (0.88–0.97) | 0.31 | 94.62 | 83.33 | 92.63 | 87.50 | 91.11 |
Data of AUC are presented as 95% confidence intervals. AUC, area under the ROC curve; CI, confidence interval; PPV, positive predictive value; NPV, negative predictive value; AP, arterial phase; VP, venous phase; CT40keV, the value of 40 keV monochromatic images; λHU, the slope of the spectral HU curve; NIC, the normalized iodine concentration; HU, Hounsfield unit.