FIGURE 5.

Effects of Eomes on the progression of esophageal cancer in vivo. A, Tumor proliferation rate of subcutaneous vaccination with KYSE450 with Eomes knockdown. B, Tumor tissue weight of xenografts harvested after tumor challenge. C, Detection of Eomes expression in xenograft tumor tissues by qRT‐PCR. D, Detection of CCL20 expression in xenograft tumor tissues by qRT‐PCR. E, Research summary: Eomes through the CCL20‐CCR6 pathway and chemotaxis of Tregs in the ESCC tumor microenvironment affects the progression of esophageal cancer. Data are presented as mean ± SD. *P < .05, **P < .01