FIGURE 2.

Effect of SB431542 and isoxsuprine on the migration and proliferation of SAS cells. A, B, SAS cells were cultured in the absence (−/control) or presence of 10 μmol/L SB431542 or various concentrations of isoxsuprine (0.1, 1, and 10 μmol/L) for 72 h. SAS cells migrated for 48 h were stained (A) and counted (B). Scale bar: 200 µm. (C) SAS cells were grown for 72 h in the absence (−) or presence of 10 μmol/L SB431542 or 10 μmol/L isoxsuprine and counted. Data are represented as mean ± SD **P < 0.01, ***P < 0.001; ns, not significant