Table 1.
Top 20 differentially expressed genes in McA‐RH7777 cells receiving sublethal irradiation
| Gene symbol | Fold change (RH6Gy‐SR/RH6Gy‐SnonR) |
|---|---|
| Upregulated | |
| ABCG5 | 191.3249 |
| WDR11 | 183.7237 |
| LOC498084 | 174.045 |
| DHX32 | 165.1955 |
| LAMTOR5 | 161.2523 |
| PRP2L1 | 149.0754 |
| SNRPC | 148.8021 |
| KCNJ16 | 129.4143 |
| OPRM1 | 124.6007 |
| OLR672 | 122.0062 |
| Downregulated | |
| OLR729 | 0.0044 |
| TELO2 | 0.0049 |
| GABRE | 0.0082 |
| LOC688649 | 0.0097 |
| AKR1B10 | 0.0100 |
| KCNIP3 | 0.0104 |
| KLHL24 | 0.0107 |
| OLR1492 | 0.0107 |
| PVR | 0.0111 |
| ZC3H12C | 0.0113 |
Gene expression changes in RH6Gy irradiated supernatant (SR) cells (McA‐RH7777 cells treated with irradiated conditioned media [CM] cultures, then received 6 Gy irradiation) compared with RH6Gy nonirradiated supernatant (SnonR) cells (McA‐RH7777 cells treated with nonirradiated CM cultures, then received 6 Gy irradiation); 726 genes with a fold change greater than 3 were identified. The 20 genes shown in the table exhibited the most dysregulated changes.